GO:0035872 biological_process nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
| PAG Title | GO:0035872 biological_process nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway |
| PAG ID | TAX023131 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A series of molecular signals generated as a consequence of a nucleotide-binding domain, leucine rich repeat containing receptor (NLR) binding to one of its physiological ligands. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. The NLR signaling pathway begins with binding of a ligand to a NLR receptor and ends with regulation of a downstream cellular process. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 2,884 |
| Information Content | Rich |
| Other IDs | GO:0035872 |
| Base PAG ID | TAX023131 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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